Comparison 4. Aztreonam plus clindamycin versus any other regimen.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Treatment failure	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
1.1 Aztreonam plus clindamycin versus trospectomycin plus aztreonam	2	422	Risk Ratio (M‐H, Fixed, 95% CI)	1.49 [0.78, 2.84]
1.2 Aztreonam plus clindamycin versus gentamicin plus clindamycin	2	181	Risk Ratio (M‐H, Fixed, 95% CI)	0.45 [0.12, 1.67]
2 Severe complication	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 Aztreonam plus clindamycin versus gentamicin plus clindamycin	1	62	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Wound infection	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 Aztreonam plus clindamycin versus gentamicin plus clindamycin	1	117	Risk Ratio (M‐H, Fixed, 95% CI)	1.09 [0.07, 17.00]
4 Allergic reaction	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
4.1 Aztreonam plus clindamycin versus gentamicin plus clindamycin	2	181	Risk Ratio (M‐H, Fixed, 95% CI)	1.71 [0.23, 12.54]
5 Diarrhea	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 Aztreonam plus clindamycin versus gentamicin plus clindamycin	1	119	Risk Ratio (M‐H, Fixed, 95% CI)	2.10 [0.20, 22.58]
6 Length of stay	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
6.1 Aztreonam plus clindamycin versus gentamicin plus clindamycin	1	119	Mean Difference (IV, Fixed, 95% CI)	‐0.45 [‐1.15, 0.25]