| Methods |
Randomized trial
Study period: September 1987 through July 1988 |
| Participants |
Inclusion criteria: women with clinical findings of upper genital tract infection in the puerperium
Setting: university hospital, Denver, Colorado, USA
Number of participants: n = 36 |
| Interventions |
Ampicillin/sulbactam 2 g/1 g iv every 6 hours (n = 18) vs clindamycin 900 mg iv every 8 hours and gentamicin 1.5 mg/kg every 8 hours (n = 18) |
| Outcomes |
Therapeutic failure
Adverse reactions
Calculated daily costs (drug and pharmacy). Sulbactam/ampicillin USD 91.20 vs clindamycin/gentamicin USD 116.97 |
| Notes |
Included 23 participants with endometritis following cesarean birth and 13 with endometritis following vaginal birth
Pharmaceutical sponsorship ‐ probable |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
States “randomised” without further description |
| Allocation concealment (selection bias) |
Unclear risk |
Not stated |
| Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
Not stated |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
Not stated |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No drop‐outs described |
| Selective reporting (reporting bias) |
Unclear risk |
The protocol is not available, insufficient information to permit judgment |
| Other bias |
Low risk |
The study appears to be free of other sources of bias |
