| Methods |
Randomized trial
Study period: not stated |
| Participants |
Inclusion criteria: women with clinical diagnosis of postcesarean endometritis
Setting: not stated (presumably university hospital Jackson, Mississippi, USA)
Number of participants: n = 100 |
| Interventions |
Gentamicin 1.5 mg/kg iv every 8 hours plus clindamycin 900 mg iv every 8 hours (n = 44) vs gentamicin 5 mg/kg iv every 24 hours plus clindamycin 900 mg iv every 8 hours (n = 41) |
| Outcomes |
Therapeutic failure
Nephrotoxicity
Mean length of stay |
| Notes |
All participants were postcesarean births
This is a published abstract; insufficient information provided on excluded women to perform intention‐to‐treat analysis
Pharmaceutical sponsorship ‐ probable |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
States "randomized" without further explanation |
| Allocation concealment (selection bias) |
Unclear risk |
No allocation procedure was reported |
| Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
No discussion of blinding patients, physicians or outcome abstractors |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
No discussion of blinding patients, physicians or outcome abstractors |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
85 out of 100 (85%) remained in the analysis . Reasons for drop out were not stated |
| Selective reporting (reporting bias) |
Unclear risk |
The protocol is not available, insufficient information to permit judgment |
| Other bias |
Unclear risk |
Only abstract available for assessment |
