Marhic 1991.
Methods | Randomised controlled trial comparing 4 g of troxerutin (Hydroxyethylrutoside) in 2 doses with a placebo. | |
Participants | Inclusion criteria: pregnant women in their second trimester with symptomatic vulvar varicosities and venous insufficiency in their lower extremities. Exclusion criteria: none stated. |
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Interventions | intervention group: 4 g of troxerutin (Hydroxyethylrutoside) in 2 doses. Comparision group: placebo. Study duration: 4 months. |
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Outcomes | Pain and discomfort from vulvar varicosities. Pain due to limb venous insufficiency. Heaveness in the legs. |
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Notes | The trial examined the efficacy of troxerutin in gynaecology and obstetric. In this review, only information about obstetric populations was included. Data not in useable format. Not able to trace the authors. Sample size: 30 women. Country: France. Study years: not stated. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Sequence generation not described. |
Allocation concealment (selection bias) | Unclear risk | Allocation concealment not described. |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Study described as double blind. |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Blinding of outcome assessor not described. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 30 women randomised. Data for all women presented. |
Selective reporting (reporting bias) | Low risk | Selective reporting not apparent. |
Other bias | Low risk | None noted. |