Skip to main content
. 2009 Jan 21;2009(1):CD001077. doi: 10.1002/14651858.CD001077.pub2

Comparison 1. Restricted versus liberal oxygen therapy (all preterm/LBW infants) in early neonatal period.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death (any) 2 298 Risk Ratio (M‐H, Fixed, 95% CI) 1.23 [0.80, 1.90]
2 Cicatricial RLF (any grade) in survivors 2 221 Risk Ratio (M‐H, Fixed, 95% CI) 0.26 [0.11, 0.58]
3 Vascular RLF (any stage) in survivors 3 341 Risk Ratio (M‐H, Fixed, 95% CI) 0.34 [0.25, 0.46]
4 Vascular RLF (severe stages) in survivors 1 157 Risk Ratio (M‐H, Fixed, 95% CI) 0.38 [0.17, 0.85]
5 Cicatricial RLF (severe grades) in survivors 2 277 Risk Ratio (M‐H, Fixed, 95% CI) 0.19 [0.07, 0.50]
6 Death or vascular (RLF (any stage) 2 298 Risk Ratio (M‐H, Fixed, 95% CI) 0.59 [0.48, 0.72]
7 Death or cicatricial RLF (any grade) 2 298 Risk Ratio (M‐H, Fixed, 95% CI) 0.77 [0.56, 1.07]
8 Cicatricial RLF (severe grades) in survivors (excluding Patz 1954) 1 157 Risk Ratio (M‐H, Fixed, 95% CI) 0.32 [0.11, 0.93]
9 Vascular RLF (any stage) in survivors (excluding Patz 1954) 2 221 Risk Ratio (M‐H, Fixed, 95% CI) 0.36 [0.26, 0.51]