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. 2020 Feb 24;10:57. doi: 10.3389/fcimb.2020.00057

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Copyright © 2020 Melkus, Le, Siddiqui, Molehin, Zhang, Lazarus and Siddiqui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune cell lineage analysis during Schistosoma infection and PZQ therapy. Baboons were infected with 200 S. mansoni cercariae five times at weekly intervals (A). Peripheral blood (n = 4) was collected at the indicated time points and analyzed for changes in myeloid and lymphoid immune cell lineages by flow cytometry (B). Statistical analysis was completed using non-parametric Mann-Whitney U-test and findings were determined to be statistically significant at *p < 0.05. Bars represent means with standard error of the mean.