. Author manuscript; available in PMC: 2020 Oct 1.

Published in final edited form as: Alzheimer Dis Assoc Disord. 2019 Oct-Dec;33(4):327–330. doi: 10.1097/WAD.0000000000000339

Table 1:

Demographic characteristics by disease series in a series of 3,058 patients and 5,089 controls

Series	Total Individuals	R47H carriers	% Female	% European	Average Age at Onset
AD	1157	22 (1.90%)	56.4	67.9	63.9 ±10.7
FTD	751	7 (0.93%)	45.5	92.4	58.9 ±9.4
MCI	610	4 (0.66%)	55.5	75.1	63.0 ±10.7
PSP-S	391	1 (0.26%)	46.9	93.1	64.3 ±7.5
CBS	123	1 (0.81%)	48.8	91.2	61.0 ±7.4
ALS	26	1 (3.85%)	34.6	83.3	55.9 ±10.4
Overall	3058	36 (1.18%)	51.9	79.1	62.0 ±10.2
Control	5089	22 (0.43%)	57.4	68.5	N/A

AD: Alzheimer’s disease, FTD: frontotemporal dementia, MCI: mild cognitive impairment, PSP-S: progressive supranuclear palsy syndrome, CBS: corticobasal syndrome, ALS: amyotrophic lateral sclerosis. Overall refers to the combined neurodegenerative patient samples.

Age of onset was available in: AD (674/1157), FTD (524/751), MCI (245/610), PSP-S (121/391), CBS (112/123), ALS (19/26).

Gender was available in: AD (1085/1157), FTD (672/751), MCI (609/610), PSP-S (382/391), CBS (123/123), ALS (26/26), Controls (4550/5089).

Ancestry was available in: AD (1085/1157), FTD (605/751), MCI (594/610), PSP-S (363/391), CBS (113/123), ALS (24/26), Controls (4333/5089).