Table 3:
Regression analysis for SNPs within HLA-DQA1, NRXN1, CNTNAP2 and CDH4.
| Neuropsych variable | r square | Adjusted r square | F | p | |
|---|---|---|---|---|---|
| HLA-DQA1 rs9272105 | All patients with psychosis | ||||
| Premorbid IQ | 0.01 | 0.007 | 3.7 | 0.055 | |
| Logical memory 2 | 0.035 | −0.002 | 0.44 | 0.508 | |
| SART Reaction time | 0.028 | 0.021 | 4.0 | 0.019 | |
| PAL Total errors | 0.003 | 0.001 | 0.898 | 0.344 | |
| Patients with SZ + SZA only | |||||
| Premorbid IQ | 0.021 | 0.017 | 6.25 | 0.013 | |
| Logical memory 2 | .009 | .005 | 2.38 | 0.123 | |
| SART Reaction time | 0.036 | 0.027 | 3.98 | 0.02 | |
| PAL Total errors | 0 | −0.003 | 0.083 | 0.773 | |
| NRXN1 rs1819972 | All patients with psychosis | ||||
| Premorbid IQ | 0 | −0.002 | 0 | 0.996 | |
| Logical memory 2 | 0.032 | −0.002 | 0.386 | 0.535 | |
| SART Reaction time | 0.012 | 0.008 | 3.538 | 0.061 | |
| PAL Total | 0.008 | 0.005 | 2.819 | 0.094 | |
| Patients with SZ + SZA only | |||||
| Premorbid IQ | 0 | −0.003 | 0 | 0.983 | |
| Logical memory 2 | .003 | −0.001 | .831 | 0.363 | |
| SART RT | 0.012 | 0.008 | 2.81 | 0.095 | |
| PAL Total errors | 0.011 | 0.007 | 3.1 | 0.079 | |
| CNTNAP2 rs1548743 | All patients with psychosis | ||||
| Premorbid IQ | 0 | −0.002 | 0.188 | 0.664 | |
| Logical memory 2 | 0.01 | −0.003 | 0.038 | 0.845 | |
| SART Reaction time | 0 | −0.003 | 0.066 | 0.797 | |
| PAL Total errors | 0.006 | 0.004 | 2.43 | 0.119 | |
| Patients with SZ + SZA only | |||||
| Premorbid IQ | 0.001 | −0.002 | 0.271 | 0.603 | |
| Logical memory 2 | 0.03 | 0.001 | 0.324 | 0.57 | |
| SART Reaction time | 0 | −0.004 | 0.005 | 0.946 | |
| PAL Total | 0.008 | 0.005 | 2.4 | 0.122 | |
| CDH4 rs2427104 | All patients with psychosis | ||||
| Premorbid IQ | 0 | −0.002 | 0.154 | 0.695 | |
| Logical memory 2 | 0.042 | 0.002 | 0.656 | 0.419 | |
| SART Reaction time | 0.001 | −0.002 | 0.311 | 0.577 | |
| PAL Total errors | 0 | −0.002 | 0.113 | 0.737 | |
| Patients with SZ + SZA only | |||||
| Premorbid IQ | 0.001 | −0.002 | 0.411 | 0.522 | |
| Logical memory 2 | 0.085 | 0.007 | 2.19 | 0.14 | |
| SART Reaction time | 0.003 | −0.001 | 0.785 | 0.377 | |
| PAL Total errors | 0 | −0.003 | 0.055 | 0.815 | |