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. Author manuscript; available in PMC: 2020 Mar 2.
Published in final edited form as: Cytokine. 2018 Aug 23;111:146–153. doi: 10.1016/j.cyto.2018.08.009

Fig. 4.

Fig. 4.

Differential expression of epithelial genes triggered by IL33 correlates with a subset of genes involved in diseases of the digestive system. (A) Vfl33 and WT IEC were analyzed by RNA-Seq/edgeR using a paired design (n = 3–4/group). Plot of logFC (log fold change) versus logCPM (log counts per million) of all detected transcripts. Points are colored according to expression status: non-significant genes (gray) and significant genes (155 genes; Q < 0.05 and −2 > fold change > 2; red). (B) NextBio meta-analysis showed that the mRNA expression profile of Vfl33 IEC vs WT IEC negatively correlated with various digestive system diseases. The correlated diseases are shown with the corresponding significant scores as well as the number of biosets within each disease. Columns are colored according to correlation with query: positive correlation (red) and negative correlation (blue).