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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Exp Neurol. 2019 Dec 16;325:113075. doi: 10.1016/j.expneurol.2019.113075

Figure 7. Vesicular GABA transporter decreases in AOF females in mPFC following CIH exposure.

Figure 7.

(A & B) Representative images depicting the localization of v-GAT-labeled terminal fields in PL and IL mPFC of an AOF control (A) and an AOF 10% CIH (B) female mouse. Moderate CIH decreased v-GAT-ir density in the PL and IL mPFC in AOF mice. (C & D) Representative images showing higher magnification of v-GAT-ir in the PL of an AOF control (C) and an AOF 10% CIH (D) female mouse. Arrows show examples of vGAT-labeled processes. (E & F) Bar graphs show the relative v-GAT-ir density in the PL (E) and IL (F) of the four layers of mPFC. AOF females with mild CIH show decreased v-GAT-ir density in the PL (significant in layers 1, 3, and 4) and IL (significant in layers 2, 3, and 4) mPFC. N = 5 animals per group. Scale bars = A,B 100 μm; C,D = 20 μm.