Table 1:
Dataset Description
| Variables | Sub-variables | CCF (D1) (N%) | UPenn (D2) (N%) | TCGA (D3) (N%) | P- value |
|---|---|---|---|---|---|
| Number of patients | 329 | 114 | 82 | ||
| Treatment | Surgery Alone | 256 (D1s) (77·81%) | 81 (D2s) (71·05%) | 58 (D3s) (70·73%) | p>0·05 |
| ACT | 73 (D1a) (22·18%) | 33 (D2a) (28·94%) | 24 (D2a) (29·26%) | ||
| Age at Dx | <=65 | 86 (26·14%) | 46 (40·35%) | 34 (41·46%) | p>0·05 |
| >65 | 142 (43·16%) | 68 (59·65%) | 48 (58·53%) | ||
| Unknown | 101 (30·69%) | 0 (0%) | 0 (0%) | ||
| Gender | Male | 115 (34·95%) | 38 (33·33%) | 56 (68·29%) | p>0·05 |
| Female | 113 (34·34%) | 76 (66·66%) | 26 (31·70%) | ||
| Unknown | 101 (30·69%) | 0 (0%) | 0 (0%) | ||
| Smoking Status | Current | 85 (25·83%) | 6 (5·26%) | 17 (20·73%) | p>0·05 |
| Previous Use | 209 (63·52%) | 82 (71·93%) | 47 (57·32%) | ||
| Never Used | 32 (9·73%) | 26 (22·80%) | 18 (21·95%) | ||
| Unknown | 3 (0·91%) | 0 (0%) | 0 (0%) | ||
| Stage | Stage 1 | 276 (83·89%) | 89 (78·07%) | 57 (69·51%) | p>0·05 |
| Stage 2 | 53 (16·11%) | 33 (28·94%) | 25 (30·48%) | ||
| LVI | Present | 98 (29·79%) | Unknown | 5 (6·09%) | P>0·05 |
| Absent | 214 (65·04%) | 74 (90·24%) | |||
| Unknown | 17 (5·16%) | 3 (3·65%) | |||
| N-descriptor | 0 | 255 (77·51%) | Unknown | 69 (84·14%) | p>0·05 |
| 1 | 46 (13·98%) | 13 (15·85%) | |||
| Unknown | 28 (8·51%) | 0 (0%) | |||
| T- descriptor | 1 | 158 (48·02%) | Unknown | 38 (46·34%) | p>0·05 |
| 2 | 88 (26·74%) | 31 (37·80%) | |||
| 3 | 8 (2·43%) | 13 (15·85%) | |||
| Unknown | 75 (22·79%) | 0 (0%) | |||
| Margin Status | Negative | 323 (98.17%) | 144 (100%) | Unknown | P<0.05 |
| Positive | 6 (1.82%) | 0 (0.00%) | |||
| Tumor | RUL | 128 (38.90%) | 35 (30.70%) | 26 (31.71%) | P<0.05 |
| Location | RLL | 45 (13.67%) | 22 (19.29%) | 11 (13.41%) | |
| RML | 15 (4.56%) | 4 (3.51%) | 8 (9.75%) | ||
| LUL | 94 (28.57%) | 32 (28.07%) | 23 (28.05%) | ||
| LLL | 47 (14.28%) | 21 (18.42%) | 14 (17.07%) | ||
| Type of | Lobectomy | 64 (19.45%) | 55 (48.24%) | Unknown | P<0.05 |
| surgery | Sublobar | 234 (71.12%) | 49 (42.98%) | ||
| Pneumonectomy | 15 (4.56%) | 1 (0.88%) | |||
| segmentectomy | 16 (4.86%) | 0 (0.00%) | |||
| EGFR | Mutatnt | 25 (7.59%) | 36 (31.58%) | 17 (20.73%) | P<0.05 |
| Mutation | Wildtype | 95 (28.87%) | 78 (68.42%) | 54 (65.85%) | |
| Unknown | 209 (63.52%) | 0 (0.00%) | 11 (13.41%) | ||
| KRAS | Mutatant | 2 (0.61%) | 32 (28.07%) | 17 (20.73%) | P<0.05 |
| Mutation | Wildtype | 3 (0.91%) | 82 (71.93%) | 54 (65.85%) | |
| Unknown | 324 (98.48) | 0 (0.00%) | 11 (13.41%) | ||
| Histology | Adenocarcinoma | 211 (64·13%) | 114 (100%) | 82 (100%) | P>0·05 |
| Squamous cell carcinoma | 93 (28·26%) | 0 (0.00%) | 0 (0%) | ||
| Other | 21 (6·38%) | 0 (0.00%) | 0 (0%) | ||
| Unknown | 4 (1·21%) | 0 (0.00%) | 0 (0%) | ||
| Recurrence | Recurrence | 71 (21·58%) | 25 (21·92%) | 26 (31·70%) | p>0·05 |
| Non-Recurrence | 258 (78·41%) | 89 (78·07%) | 56 (68·29%) |