Table 1. Cox proportional hazard regression model results.

The model includes common prognostic factors including age at diagnostics (Age.at.Dx), white blood cell count (WBC) and cytogenetic categories (Cytogenetics-Intermediate, Cytogenetics-Unfavorable). The 13 protein signatures were grouped in three categories: Favorable (Signature 6,7,12), Intermediate (Signature 1,2,5,8,9,11,13), Unfavorable (Signature 3,4,10). SE: Standard Error. Sample size n = 205.

	Overall Survival					Remission Duration
	beta	SE of beta	hazard ratio	z-score	p-value	beta	SE of beta	hazard ratio	z-score	p-value
Age.at.Dx	0.038	0.006	1.039	6.50	8.2e-11	0.015	0.008	1.016	1.98	0.048
WBC	0.006	0.001	1.006	4.33	1.5e-5	0.007	0.002	1.007	3.38	0.001
Cytogenetics-Intermediate	1.107	0.405	3.026	2.74	0.006	0.659	0.411	1.933	1.60	0.109
Cytogenetics-Unfavorable	1.488	0.404	4.428	3.69	2.3e-4	1.100	0.404	3.004	2.72	0.007
Signature-Favorable	−0.950	0.252	0.387	−3.77	1.7e-4	−1.907	0.474	0.149	−4.02	5.8e-5
Signature-Intermediate	−0.737	0.207	0.478	−3.57	3.6e-4	−0.821	0.293	0.440	−2.80	0.005