Table 1. Demographics of study populations.
| Discovery (N = 783) | Replication (N = 538) | ||||
|---|---|---|---|---|---|
| CARE (N = 150) | ACRN (N = 220) | BioVu (N = 413) | CAMP (N = 176) | PMRP (N = 362) | |
| Cases | |||||
| Sample size (N) | 113 | 24 | 270 | 58 | 229 |
| Sex (% male) | 58.4 | 29.2 | 27.4 | 69 | 29.7 |
| Age*, yrs. (mean [range]) | 12.6 [9.2–17.2] | 35.8 [14.0–55.8] | 34.8 [20.0–68.5] | 7.3 [2.3–15.8] | 24.1 [5–46] |
| BMI (mean, [range]) | 20.9 [14.5–38] | 25.2 [18.8–35.7] | 31.2 [17.1–45.3] | 18.5 [14.2–28.5] | 26.9 [8.4–56.1] |
| Controls | |||||
| Sample size (N) | 37 | 196 | 143 | 118 | 133 |
| Sex (% male) | 54.1 | 46.2 | 32.9 | 60.2 | 29.3 |
| Age*, yrs. (mean [range]) | 13.4 [10.0–16.8] | 33.2 [14.4–65.2] | 31.4 [20.0–65.5] | 11.3 [6–17.8] | 25.6 [8–44] |
| BMI (mean, [range]) | 21.7 [16.3–41.1] | 25.2 [17.0–41.6] | 28.7 [16.5–43.3] | 20.7 [13.6–46.2] | 26.1 [15.4–49.5] |
*Age refers to age at event, for cases in PMRP and BioVu, or age at the final study visit, for all controls, and for the cases in CARE, ACRN and CAMP.