Table 1.
Association between immunohistochemical FAM136A status and clinicopathological parameters in 177 lung carcinomas.
| Clinical pathological parameters and the status of cytoplasmic FAM136A expression by immunohistochemistry | ||||
|---|---|---|---|---|
| FAM136A, n (%) |
||||
| Variables | Total, n | Positive | Negative | p-Value |
| Age(years) | ||||
| <60 | 102 | 44 (42.16) | 58 (57.84) | 0.54 |
| ≥60 | 75 | 35 (46.75) | 40 (53.25) | |
| Gender | ||||
| Male | 107 | 50 (46.30) | 57 (53.70) | 0.76 |
| Female | 70 | 29 (40.85) | 41 (59.15) | |
| History of smoking | ||||
| Yes | 74 | 35 (46.05) | 41 (53.95) | 0.674 |
| No | 103 | 44 (42.72) | 57 (57.28) | |
| Pathology | ||||
| Adenocarcinoma | 133 | 52 (40.0) | 81 (60.0) | 0.051 |
| SCC | 44 | 27 (56.82) | 17 (43.18) | |
| Tumor size | ||||
| T1 | 102 | 48 (61.7) | 54 (54.2) | 0.035* |
| T2/3/4 | 75 | 31 (38.3) | 44 (45.8) | |
| Lymph node metastasis | ||||
| N0 | 100 | 35 (42.0) | 65 (58.0) | 0.046* |
| N1/N2 | 77 | 44 (57.1) | 33 (42.9) | |
| AJCC stage | ||||
| Ⅰ | 88 | 28 (35.4) | 60 (61.2) | 0.001* |
| Ⅱ-Ⅲ | 89 | 51 (64.6) | 38 (38.8) | |
*: Data are presented as mean ± SD. All other values represent the number of cases. Statistical analysis was evaluated by the Student’s t-test or a cross-table using the chi-square test. P value<0.05 was considered significant and borderline significant, and are listed in bold. SCC: squamous cell carcinoma.