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Treatment with 1/2 the minimal inhibitory concentration of ceftazidime (CAZ) increased the amount of lipopolysaccharide (LPS) carried by bacterial membrane vesicles (BMVs) but not the amount in supernatants, compared to treatment with imipenem (IMP). LPS was detected with an anti-LPS antibody by western blot analysis. Cell lysate of ATCC 17978 was used as a positive control.
