Table 2.

The proteins with the greatest decrease in the bacterial membrane vesicle (BMVs) from Acinetobacter baumannii induced by antimicrobial treatment when compared to BMVs collected from an untreated LB culture.

CAZ-BMV			IMP-BMV
Annotation and locus	Category	Fold change (CAZ-BMV/LB-BMV)	Annotation and locus	Category	Fold change (IMP-BMV/LB-BMV)
Putative major capsid protein [A0A062EZ25_ACIBA]	Phage protein	0.57897	Putative major capsid protein [A0A062EZ25_ACIBA]	Phage protein	0.380593
Uncharacterized protein [A0A062ID26_ACIBA]	Other	0.628035	Uncharacterized protein [A0A009GER5_ACIBA]	Other	0.424309
Uncharacterized protein [B0VT25_ACIBS]	Other	0.956489	Succinate dehydrogenase iron-sulfur subunit [A0A009TAP4_ACIBA]	Other	0.545266
50S ribosomal protein L5 [A0A0B2XT25_ACIBA]	Peptide biosynthetic process	0.988407	50S Ribosomal protein L15 [A0A062DKQ2_ACIBA]	Peptide biosynthetic process	0.545366
			Uncharacterized protein [A0A009SPB4_ACIBA]	Other	0.545674
			30S Ribosomal protein S3 [A0A022IKC9_ACIBA]	Peptide biosynthetic process	0.555256
			Small GTP-binding domain protein [A0A062L8H2_ACIBA]	Other	0.561308
			ATP synthase subunit b [A0A009SUU5_ACIBA]	Other	0.572067
			Bacterioferritin [A0A1S2FNX1_ACIBA]	Iron chelate	0.593761
			50S ribosomal protein L6 [A0A022II07_ACIBA]	Peptide biosynthetic process	0.604319
			Elongation factor Tu [A0A062IYJ9_ACIBA]	Other	0.604711
			50S ribosomal protein L5 [A0A0B2XT25_ACIBA]	Peptide biosynthetic process	0.625656
			50S ribosomal protein L20 [A0A062IGI6_ACIBA]	Peptide biosynthetic process	0.625876
			NADH-quinone oxidoreductase subunit C [A0A062M7K5_ACIBA]	Other	0.62749
			CTP synthase [A0A062FS34_ACIBA]	Other	0.643215

LB-BMV indicates BMVs derived from A. baumannii grown in Luria-Bertani broth without antibiotic treatment. CAZ-BMV indicates BMVs derived from A. baumannii grown in Luria-Bertani broth with ceftazidime. IMP-BMV indicates BMVs derived from A. baumannii grown in Luria-Bertani broth with imipenem.