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. 2020 Feb 5;7(2):e675. doi: 10.1212/NXI.0000000000000675

Figure 1. GDF-15 concentrations in serum and CSF of patients with MS and controls.

Figure 1

Concentration of GDF-15 in healthy controls, patients with NIND, patients with rMS, and patients with OIND in serum (A) and CSF (B) (median and IQRs). Correlation between serum and CSF GDF-15 concentrations in pooled patients with NIND, rMS, and OIND (C). Concentration of GDF-15 in patients with rMS with or without disease activity at the time point of sampling in serum (D) and CSF (E) (median and IQRs). ***p < 0.001. GDF-15 = growth differentiation factor 15; HC = healthy control; IQR = interquartile range; NIND = noninflammatory neurologic diseases; OIND = other inflammatory neurologic diseases; rMS = relapsing MS.