Table 1:
Patient/Age (yr)/Sex | Neurologic Features | WM Involved in Delayed Encephalopathy on MRI | Time (days) |
||
---|---|---|---|---|---|
Lucid | To MRI | To Testing | |||
1/57/M | Acute: coma, conscious in 2 days; delayed: impaired memory, personality change, parkinsonism, general weakness | Globus pallidus, frontal, parietal, temporal, occipital | 12 | 12 | 22 |
2/44/M | Acute: coma, conscious in ≤1 day; delayed: impaired cognition and memory | Globus pallidus, frontal, parietal | 42 | 83 | 44 |
3/26/F | Acute: coma, conscious in a few days; delayed: impaired memory, parkinsonism, amnesia, bad temper | Frontal, parietal | 13 | 120 | 115 |
4/35/M | Acute: coma; delayed: impaired memory, inattention, personality change, amnesia | Parietal, occipital | 20 | 31 | 24 |
5/34/M | Acute: coma, conscious in 1 week; delayed: ataxia, impaired memory, ideomotor apraxia | Globus pallidus, frontal, parietal | 7 | 393 | 383 |
6/62/M | Acute: coma, conscious in ≤1 day; delayed: confusion, impaired cognition, apraxia, amnesia, parkinsonism | Globus pallidus, frontal, parietal, occipital | 25 | 4 | 3 |
7/41/F | Acute: coma; delayed: parkinsonism, dysmetria, dyssynergia, urine retention, difficulty defecating | Globus pallidus, frontal, parietal | 7 | 4 | 15 |
8/24/F | Acute: coma; delayed: ataxia, impaired cognition | Globus pallidus, frontal, parietal | 20 | 107 | 106 |
9/41/F | Acute: coma; delayed: disorientation, incoherent speech, dysexecution, behavioral changes, acute dystonia | Globus pallidus, frontal, parietal | 19 | 26 | 8 |
10/43/M | Acute: coma, conscious in ≤1 day; delayed: impaired memory and cognition, parkinsonism | Globus pallidus, frontal, parietal | 17 | 30 | 18 |
11/48/M | Acute: disturbed consciousness in 1 day; delayed: depression, parkinsonism | Globus pallidus | 10 | 3 | 2 |
12/36/F | Acute: disturbed consciousness in 1 day; delayed: amnesia, apraxia | Globus pallidus, parietal, occipital | 23 | 414 | 414 |
13/37/F | Acute: coma; delayed: impaired memory and cognition | Frontal, parietal, occipital | 6 | 55 | 7 |
14/41/M | Acute: coma; delayed: ataxia, disorientation, urinary incontinence | No obvious lesion | 15 | 442 | 423 |
Note:—MRI indicates MR imaging.