Table 2:

Associations between baseline flow characteristics and progression of MR imaging abnormalities

	Lower TCBF	Higher TCBF	Lower CVR	Higher CVR
	(< 584 mL/min)	(≥ 584 mL/min)	(< 65%)	(> 65%)
	(n = 12)	(n = 13)	(n = 7)	(n = 7)
	Mean: 485	Mean: 683	Mean: 53%	Mean: 81%
	SD: 75	SD: 86	SD: 10%	SD: 17%
Δ WMHs in % (SD)	2.8 (2.7)	2.0 (1.6)	2.9 (1.5)	0.37 (0.03)***
% Subjects with new infarcts	9/12 (75%)	9/13 (69%)	6/7 (86%)	3/7 (43%)
% Subjects with new microbleeds	4/12 (33%)	3/13 (23%)	2/7 (29%)	1/7 (14%)

Note:—CVR indicates cerebrovascular reactivity. The Student t test is used for WMHs; the Fisher Exact test, infarcts and microbleeds.

^***Difference (P < .001) between higher and lower.