Table 5:
Group dichotomization by ROC-defined CBS threshold of more than 6
| Parameter | CBS ≤6 (n = 41) | CBS >6 | P Value |
|---|---|---|---|
| Age, mean ± SD | 68 (12) | 71 (15) | .18 |
| ASPECTS, median (IQR) | 6 (3.5–7.5) | 9 (6–10) | <.0001 |
| Presenting NIHSS score, median (IQR) | 18 (14.5–21) | 13 (6.25–0.5) | .009 |
| Time to scanning (min), mean ± SD | 122 ± 63 | 137 ± 20 | .28 |
| Time to rtPA (min), mean ± SD | 142 ± 51 | 142 ± 26 | .79 |
| Post-rtPA recanalization (No.) (%) | 14 (44%) | 20 (71%) | .04 |
| Hyperglycemia (No.) (%) | 6 (14.6%) | 5 (11.4%) | .75 |
| Hypertension (No.) (%) | 9 (22.0%) | 13 (29.5%) | .47 |
| CS, median (IQR) | 2 (1–2.5) | 2.5 (2–3) | .005 |
| CBF (cm3), mean ± SD | 119 ± 47 | 78 ± 51 | <.0001 |
| CBV (cm3), mean ± SD | 49 ± 39 | 29 ± 35 | .003 |
| MTT (c cm3), mean ± SD | 119 ± 43 | 76 ± 51 | .0001 |
| rtPA dose (mg), mean ± SD | 61 ± 18 | 60 ± 14 | 0.21 |
| Final infarct size (cm3), mean ± SD | 179 ± 130 | 58 ± 98 | <.0001 |
| mRS, median (IQR) | 4 (3–6) | 2 (1–5) | .002 |
| Parenchymal hemorrhage (No.) (%) | 10 (24) | 4 (9) | .05 |
Note:—ROC indicates receiver operating characteristic.