Table 4:
Blood Pressure at Toxicity | No. Pts | Normal Coagulation Platelets, Coagulation Parameters, and No Medications (No. Pts with PRES) |
Abnormal Coagulation |
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---|---|---|---|---|---|---|---|---|---|
Intrinsic Coagulopathy Thrombocytopenia or Abnormal PT, PTT, INR (No. Pts with PRES) |
Subtherapeutic, on Medications Affecting Platelet Function or Coagulation (No. Pts with PRES) |
Therapeutic, on Medication Affecting Platelet Function or Coagulation (No. Pts with PRES) |
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W/O Hem | With Hem | W/O Hem | With Hem | W/O Hem | With Hem | W/O Hem | With Hem | ||
Normotensive (MAP ≤ 105) | 44 | 15 | 3 | 17 | 1 | 3 | 1 | 2 | 2 |
Mild HTN (MAP, 106–115) | 20 | 8 | 2 | 5 | 1 | 3 | 0 | 0 | 1 |
Severe HTN (MAP ≥ 116) | 86 | 45 | 5 | 15 | 6 | 10 | 0 | 4 | 1 |
Total | 150 | 68 | 10 | 37 | 8 | 16 | 1 | 6 | 4 |
Note:—W/O indicates without; Hem, hemorrhage; PT, prothrombin time; PTT, partial thromboplastin time; INR, international normalized ratio.