Fig 3.

A–E, basilar bifurcation aneurysm #14 (female patient; age, 40 years; survival, 41 days) with a subjective and computerized occlusion rate of 100%. A, Preinterventional anteroposterior angiogram. B and C, Enlarged details of the postembolization anteroposterior DSA. C, The aneurysmal border is outlined in red, the neck plane with red arrows. An embolized caudal part of the aneurysm protrudes over the neck plane. D and E, Enlarged details of postembolization lateral DSA projection. D, The protruding part of the aneurysm (B) can be located posteriorly to the basilar artery. On both DSA projections (C and E), no false-color labeled contrast medium inflow into the aneurysm can be discerned. F–I, Micrographs (bar 5 mm) of 2 surface-stained ground sections of aneurysm #14 through the neck region and the parent arteries (PA). F, Note the attenuated blue-stained fibrin clot (FI) in the aneurysmal center. In G, the aneurysmal sac, orifice plane, and metallic coil sections are outlined and labeled in red. No residual inflow area can be discerned and false color labeled in 3 hours. Enlarged detail (magnification 10 ×) from a consecutive ground section, showing a zone of fibrovascular repair (FVR) covering the orifice. I, Further enlarged detail (magnification 140 ×) of the rectangle in 3 hours, showing a new vessel wall (NVW) with endothelial lining (EL). In the organized thrombus, multinucleated foreign-body giant cells (FBGC) can be discerned at the outer and inner coil interfaces (arrows).