Table 4.

Univariate and Multivariate Analysis of Overall Survival in HNSCC

Variables	Univariate Analysis			Multivariate Analysis
	HR	95% CI	P value	HR	95% CI	P value
Age (≤60 vs >60)	1.633	0.839–3.181	0.149
Gender (Male vs Female)	0.692	0.338–1.416	0.313
Tumor size (≤2 vs >2 cm)	2.106	1.042–4.26	0.038
Lymph node metastasis (negative vs positive)	2.082	1.072–4.047	0.03
Differentiation (Low/Medium vs High)	0.762	0.379–1.530	0.444
TNM stage (I+II vs III)	2.020	1.016–4.019	0.045
Relapse (no vs yes)	77.27	10.475–570.006	<0.001	135.826	16.950–1088.419	<0.001
Radiotherapy (no vs yes)	0.641	0.300–1.373	0.251
Chemotherapy (no vs yes)	1.807	0.817–3.997	0.144
MAGE-A11 expression (low vs high)	2.582	1.068–6.247	0.035	6.481	2.002–20.985	0.002