Table 2.

Next generation sequencing findings of FLT3-tyrosine kinase domain mutations in cases positive for D835/I836 mutations by fragment analysis

Fragment analysis results	Next generation sequencing results
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2504 A>T; p.D835V
Positive D835/I836 substitution	c.2503 G>C; p.D835H
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2503 G>A; p.D835N;
	c.2504 A>T; p.D835V;
	c.2028 C>T; p.N676K
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2503 G>T; p.D835Y
Positive D835/I836 substitution	c.2503 G>C; p.D835H;
and internal tandem duplication	c.1827_1828ins90; p.L610_E611ins30
Positive D835/I836 substitution	c.2503 G>T; p.D835Y;
and internal tandem duplication	c.1759_1788dup; p.N587_E596dup
Positive D835/I836 3 bp deletion	c.2508_2510del; p.I836del;
and internal tandem duplication	c.1754_1795dup; p.S585_E598dup
Positive D835/I836 6 bp deletion	c.2500_2505del; p.R834_D835del;
and internal tandem duplication	c.1744_1830dup; p.T582_L610dup
Positive D835/I836 6 bp deletion	c.2500_2505del; p.R834_D835del;
and internal tandem duplication	c.1744_1830dup; p.T582_L610dup
Positive D835/I836 substitution	c.2503 G>T; p.D835Y;
and internal tandem duplication	c.1786_1806dup; p.E596_K602dup
Positive D835/I836 substitution	c.2503 G>T; p.D835Y;
and internal tandem duplication	c.1743_1802dup; p.T582_L601dup
Positive D835/I836 substitution	c.2504 A>T; p.D835V;
and internal tandem duplication	c.1837_1837 + 1ins57; p.F612_G613ins19