TABLE 4.
Self-assembled DNA nanostructures as drug delivery vectors.
| Type of DNA nanostructure | Drug (Disease) | In vitro | References |
| Tetrahedron | Doxorubicin (Cancer) | MDA-MB 468, MCF-7 cells | Setyawati et al., 2016 |
| Icosahedron 30 | Doxorubicin (Cancer) | Epithelial cancer cells | Chang et al., 2011 |
| Pyramidal nanostructure | Doxorubicin (Cancer) | MDA-MB-231, HepG2, LoVo LoVo-R | Kumar et al., 2016 |
| Triangular prisms | Doxorubicin (Cancer) | MCF-7 breast cancer cells | Chan et al., 2016 |
| Crosslinked junctions | Doxorubicin (Cancer) | CCRF-CEM, Ramos, K562, K562/D | Wu et al., 2013 |
| Concatamers | Doxorubicin (Cancer) | Ramos, CEM cells, mouse model | Zhu et al., 2013b |
| Nanoflowers | Doxorubicin (Cancer) | Ramos, CEM cells, mouse model, MCF-7, HeLa | Zhu et al., 2013a; Hu et al., 2014 |
| Cocoon | Doxorubicin (Cancer) | MCF-7 cells | Sun et al., 2014 |
| Triangular origami, Rectangular origami, Origami nanotubes | Doxorubicin (Cancer) | MCF-7, MDA-MB-231 cells | Jiang et al., 2012; Zhang et al., 2014 |
| Origami nanorods | Daunorubicin (Cancer) | HL-60 cells | Halley et al., 2016 |
| Origami nanoparticle superstructures | Doxorubicin (Cancer) | U87 cells | Yan et al., 2015 |