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. 2020 Mar 2;10:3800. doi: 10.1038/s41598-020-60728-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Uptake of 1-L-[¹⁸F]FETrp in mouse brain. (A) Representative coronal PET images of a Smo/Smo mouse displaying clinical signs of a tumor (white arrow). (B) Representative coronal PET image of an age-matched control mouse (white arrow). Intravenous injection of 1.5–2.2 MBq of 1-L-[¹⁸F]FETrp in 100 μL of saline was followed by image acquisition 50–60 min post-injection. (C) Representative image of the mouse tumor (black arrow) after Hematoxylin and Eosin (H&E) staining.