TABLE 5.

Systems for incorporation of proteins into electrospun nanofibers, and their designed uses.

Protein	Nanofiber material	Purpose	References
Insulin	Polyvinyl alcohol/sodium alginate	Diabetes treatment (transmucosal delivery)	Sharma et al., 2013
	Chitosan/polyethylene oxide	Diabetes treatment (transbuccal delivery)	Lancina et al., 2017
	Fish sarcoplasmic proteins	Diabetes treatment (oral delivery)	Stephansen et al., 2015b
Peroxidase and alkaline phosphatase	Eudragit L100	Simulating oral enzyme delivery	Frizzell et al., 2017
PDGF−BB	Polyethylene oxide/polycaprolactone	Bone tissue regeneration	Briggs and Arinzeh, 2014
Growth hormone	Eudragit L100/chitosan	Oral mucositis treatment	Choi et al., 2016
EGF	Silk/polyethylene oxide	Chronic non-healing wounds treatment	Schneider et al., 2009
Glial cell-derived neurotrophic factor	Polycaprolactone-co-ethyl ethylene phosphate	Nerve regeneration	Chew et al., 2007
Nerve growth factor	Polycaprolactone-co-ethyl ethylene phosphate	Nerve regeneration	Chew et al., 2005
Nerve growth factor + monosialoganglioside	Poly (L-lactic acid-co-caprolactone)/silk fibroin	Simulating cell proliferation and differentiation	Sun et al., 2016
Vascular endothelial growth factor	Polyethylene carbonate-ε-caprolactone	Simulating cell proliferation and adherence	Zhang et al., 2012
Lysozyme	Poly (DL-lactide)/methyl cellulose	Simulating enzyme release	Yang et al., 2008
Lipase from Candida rugosa	Polyvinyl alcohol	Biocatalysis	Wang and Hsieh, 2008
Bovine serum albumin	Polyethylene oxide	Biosensing (pH)	Kowalczyk et al., 2008