Table 1.

Methods of 4NQO-induced mouse models in drinking water for OSCC.

The concentration of 4NQO (μg /mL)	Treatment period (/weeks)	Development period (/weeks)	Mouse strains	References
50	20	4	BALB/c	(70)
50	16	4 or 8	C57BL/6	(71)
100	16	4, 8, or 10	C57BL/6NCr	(13)
100	16	12	C57BL/6	(61)
100	16	12 or 13	CF-1	(72)
100	8	4, 8, 12, or 16	CBA	(73)
100	8	10	C57BL/6	(74)
100	16	6 or 12	C57BL/6	(75)