Table 1.

Effects of OFS, MET, and OFS+MET on metabolic parameters in DIO rats.

Parameter	Control	Normal	OFS	MET	OFS+MET
Weight gain (g)	56.5 ± 4.4	31.1 ± 4.1	51.7 ± 6.6	45.3 ± 3.0*	42.8 ± 3.1**
Final weight (g)	495.2 ± 19.1	373.1 ± 12.1	489.5 ± 11.8	421.8 ± 15.4*	408.2 ± 12.9**
Food intake (g/day)	25.4 ± 3.3	23.1 ± 1.2	25.2 ± 3.1	23.9 ± 2.4	22.1 ± 1.7*
Energy intake (kJ/rat/day)	276.1 ± 22.7	240.2 ± 32.3	259.1 ± 29.5	250.9 ± 19.1	248.6 ± 16.4*
Triglyceride (mg/ml)	95.1 ± 8.3	81.3 ± 3.2	89.1 ± 8.2	92.2 ± 7.1	90.5 ± 7.0
Cholesterol (mg/ml)	215.2 ± 11.2	153.3 ± 9.3	195.1 ± 11.2	175.2 ± 8.8*	170.6 ± 7.3*
HDL-cholesterol (mg/ml)	70.9 ± 4.4	95.2 ± 5.8	71.3 ± 6.1	78.3 ± 6.8	87.9 ± 2.8*
LDL-cholesterol (mg/ml)	110.1 ± 8.4	78.3 ± 6.3	106.4 ± 7.3	95.2 ± 4.7**	94.1 ± 5.9**

Values represent the mean ± S.E.M. (n = 8).

^*P < 0.05,

^**P < 0.01,

^***P < 0.001 compared to saline-treated control.