Table 3.

Area under the curve for the insulin and appetite-related hormones levels of OFS-, MET-, and OFS+MET-treated DIO rats during OGTT at week 8.

Treatment	Control	OFS	MET	OFS+MET
Insulin, nmol/L.min	60.5 ± 6.4	51.7 ± 6.6	45.3 ± 3.0*	42.8 ± 3.1**
Amylin, nmol/L.min	495.2 ± 19.1	489.5 ± 11.8	421.8 ± 15.4*	408.2 ± 12.9**
Ghrelin, nmol/L.min	25.4 ± 3.3	25.2 ± 3.1	23.9 ± 2.4	22.1 ± 1.7*
PYY, nmol/L.min	276.1 ± 22.7	259.1 ± 29.5	250.9 ± 19.1	248.6 ± 16.4*
CCK, nmol/L.min	95.1 ± 8.3	89.1 ± 8.2	92.2 ± 7.1	90.5 ± 7.0
GIP, nmol/L.min	5.2 ± 1.1	195.1 ± 11.2	175.2 ± 8.8**	181.6 ± 10.3

Values represent the mean ± S.E.M. (n = 8).

^*P < 0.05,

^**P < 0.01,

^***P < 0.001 compared to saline-treated control.