Table 1.
Patient characteristics
| Patient characteristics (n = 60) | |
|---|---|
| Age (years) | 69 ± 10 |
| Male gender (n, %) | 34 (57%) |
| Body mass index (kg/m2) | 25 ± 4 |
| Simplified Acute Physiologic Score II on inclusion | 51 ± 18 |
| ARDS severity (n, %) | |
| Mild | 21 (35%) |
| Moderate | 31 (52%) |
| Severe | 8 (13%) |
| Aetiology of ARDS (n, %) | |
| Community acquired pneumonia | 46 (77%) |
| Aspiration pneumonia with neurologic disorders | 5 (8%) |
| Ventilator associated pneumonia | 9 (15%) |
| ICU length of stay (days) | 12 [11–38] |
| Total duration of mechanical ventilation (days) | 11 [10–37] |
| Mortality at day-28 (n, %) | 26 (43%) |
| Norepinephrine | |
| Number of patients (%) | 54 (90%) |
| Dose of norepinephrine (µg/kg/min) | 0.53 [0.27–1.00] |
| Left ventricular ejection fraction (%) | 44 ± 11 |
| E/e′ ratio | 9 ± 2 |
| Ventilator settings | |
| Tidal volume (mL/kg of PBW) | 5.5 [5.0–6.0] |
| Respiratory rate (breaths/min) | 27 ± 5 |
| Fraction of inspired oxygen | 0.64 ± 0.20 |
| Patients requiring prone position (n, %) | 39 (65%) |
ARDS: acute respiratory distress syndrome; E/e′: ratio of the amplitude of the E wave over the amplitude of the e′ wave of the mitral flow with echocardiography; ICU: intensive care unit; PBW: predicted body weight