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. 2020 Mar 2;10:3804. doi: 10.1038/s41598-020-60830-9

Table 4.

Regions with unfavourable genotypes within the runs of homozygosity (ROH) with P-values < 1.0e-05 for milk, protein and fat yield (MILK, PROT and FAT, respectively).

Trait CHR Number of ROH genotypes Position (Mb) b in kg P-value Frequency of ROH genotypes (min/max)
MILK 2 5 80.54–84.81 −269.3–−279.5 4.35e-06 0.02/0.02
MILK 3 3 52.83–56.18 −321.6–−329.0 3.11e-06 0.01/0.01
MILK 5 1 89.16–90.75 −218.0 6.36e-06 0.03
MILK 5 1 96.55–102.05 −329.9 6.29e-06 0.01
MILK 6 1 115.84–117.01 −354.2 5.19e-06 0.01
MILK 13 131 44.37–58.55 −145.52–−252.0 1.23e-07 0.03/0.08
MILK 16 2 42.21–44.99 −196.7–−215.9 4.45e-06 0.03/0.04
MILK 20 22 29.23–33.31 −141.9–−217.7 9.30e-08 0.04/0.07
MILK 22 1 58.68–59.46 −341.6 2.99e-06 0.01
PROT 3 1 1.55–2.91 −6.94 4.93e-06 0.03
PROT 3 5 52.83–56.18 −9.7–−11.7 1.32e-07 0.01/0.01
PROT 6 12 72.53–80.66 −6.7–−11.6 2.60e-07 0.01/0.03
PROT 6 1 93.08–94.46 −10.47 8.91e-06 0.01
PROT 8 3 79.50–81.57 −9.8–−10.0 3.51e-06 0.01/0.01
PROT 13 176 42.93–58.55 −4.7–−8.8 3.60e-10 0.02/0.08
PROT 14 11 68.03–73.41 −5.6–−6.6 3.00e-06 0.03/0.04
PROT 16 1 43.64–46.51 −11.1 7.43e-06 0.01
PROT 16 1 52.51–53.92 −9.7 8.71e-06 0.01
PROT 22 1 57.99–59.33 −10.9 7.17e-06 0.01
FAT 5 1 87.02–88.11 −15.7 8.60e-09 0.01
FAT 5 6 109.93–118.35 −7.0–−12.8 1.56e-06 0.01/0.04
FAT 8 46 11.74–20.81 −10.5–−14.8 6.34e-08 0.01/0.02
FAT 13 1 57.32–58.55 −6.6 8.55e-06 0.04
FAT 17 2 7.14–8.03 −11.4–−11.5 2.69e-06 0.01/0.01
FAT 29 5 36.76–37.96 −3.9–−4.5 5.41e-07 0.12/0.14

Estimate b represents the difference between animals with the ROH genotype and animals without the ROH, while the P-value represents the smallest P-value for the region.