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. 2020 Mar 2;10:3791. doi: 10.1038/s41598-020-60185-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Resveratrol attenuated HFD-induced obesity. (a) Body weight growth curve of mice on HFD, normal chow diet (NCD) or HFD + RES diets. (b) Comparison of final body weight gain at the end of treatment. (c) Total white adipose tissues fat pads weight (g). (d) Adiposity index (%) was assessed as the white adipose tissues weight (g) to total body weight of mice and multiplied by 100. (e) Intraperitoneal glucose tolerance test (IPGTT), Blood glucose levels in HFD group (red square), NCD group (black circle) and HFD + RES group (blue triangle). (f) IPGTT area under the curve (AUC). (g) IPITT area under the curve (AUC) (h) Intraperitoneal insulin tolerance tests (IPITT) (n = 5). (i) Plasma glucose levels following a 4 hr fasting. All data were analyzed by one-way ANOVA, Tukey post-test. Values are expressed as means ± SD *p < 0.05, **p < 0.01, ***p < 0.001 vs. the control group. ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 vs. the HFD group. NS, not significant.