Table 2.
Characteristics of gut microbiome study participants: the AADM study.
| Characteristic |
Controls (N = 193) Mean (SD) |
Cases (N = 98) Mean (SD) |
P value* |
|---|---|---|---|
| Age (years) | 54.3 (13.3) | 59.7 (10.4) | 0.0002 |
| Body mass index (BMI, kg/m2) | 30.33 (6.09) | 32.21 (5.94) | 0.0125 |
| Percent fat mass (PFM, %) | 37.30 (9.65) | 39.62 (10.62) | 0.0641 |
| Waist circumference (cm) | 97.11 (12.56) | 101.83 (12.34) | 0.0025 |
| Waist-to-hip ratio (WHR) | 0.94 (0.08) | 0.96 (0.09) | 0.0549 |
| Glucose (mg/dl) ¥ | 82.0 (76–89) | 118 (96–157) | <0.0001 |
| Insulin (uIU/ml)¥ | 7.2 (4.4–10.5) | 9.2 (5.8–13.0) | 0.0022 |
| HOMA-IR¥ | 1.51 (0.87–2.20) | 2.67 (1.76–4.68) | <0.0001 |
| HbA1C (%) ¥ | 5.40 (5.2–5.7) | 7.4 (6.20–8.80) | <0.0001 |
| Total cholesterol (mg/dl) | 193.20 (51.34) | 201.16 (64.12) | 0.288 |
| HDL-cholesterol (mg/dl)¥ | 24 (13–37) | 31 (20–44) | 0.0272 |
| LDL-cholesterol (mg/dl) | 123.10 (44.08) | 122.72 (49.77) | 0.9478 |
| Triglycerides (mg/dl) | 94.82 (41.51) | 120.28 (59.57) | 0.0002 |
Significantly different between cases and controls at p < 0.05 in bold.
*
P-value for t-test except for variables with for Wilcoxon rank-sums test was used.
¥
indicates median (interquartile range). All other figures are mean (SD).