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DEX reduced inflammation and oxidative stress in LPS-induced AKI. (A) The content of inflammatory cytokines in serum, including IL-6 (a), TNF-α (b), IL-18 (c), IL-1β (d). (B) The content of ROS (a); the concentration of MDA (b); the activity of CAT (c); the content of GSH (d); the activity of SOD (e). Data are expressed as mean ± SEM (n = 6). *p < 0.05, **p < 0.01 versus CON group. #p < 0.5, ##p < 0.01 versus LPS group. &p < 0.05, &&p < 0.01 versus DEX + LPS group.
