Table 2.
The diagnostic performance of conventional quantitative 18F-FDG PET/MR parameters for predicting synchronous distant metastasis in pancreatic ductal adenocarcinoma patients.
| Parameter | Comparison of mean value | Receiver operating characteristic (ROC) analysis | |||||||
|---|---|---|---|---|---|---|---|---|---|
| M0 group | M1 group | p | AUC | 95% CI | p | Optimal cutoff value | Se (%) | Sp (%) | |
| Age (years) | 56.2 ± 11.8 | 58.1 ± 9.5 | 0.719† | ||||||
| Height (cm) | 167.7 ± 9.1 | 164.4 ± 5.8 | 0.373† | ||||||
| Body weight (Kg) | 64.2 ± 8.4 | 55.1 ± 9.5 | 0.07† | ||||||
| Tumor size (cm) | 3.4 ± 1.0 | 4.5 ± 1.0 | 0.039† | 0.803 | 0.543–0.952 | 0.006 | >3.3 | 81.8 | 66.7 |
| SUVmean | 2.6 ± 1.1 | 3.6 ± 1.3 | 0.149‡ | ||||||
| SUVmax | 4.5 ± 2.0 | 6.3 ± 2.3 | 0.216‡ | ||||||
| SUVpeak | 3.0 ± 1.1 | 4.8 ± 1.5 | 0.037‡ | 0.818 | 0.560–0.960 | 0.004 | >4.06 | 72.7 | 100.0 |
| SUVsd | 0.6 ± 0.3 | 0.8 ± 0.3 | 0.149‡ | ||||||
| MTV | 8.4 ± 6.1 | 20.7 ± 13.1 | 0.037‡ | 0.818 | 0.560–0.960 | 0.003 | >15.04 | 63.6 | 100.0 |
| TLG | 21.3 ± 16.7 | 67.7 ± 42.1 | 0.020‡ | 0.848 | 0.595–0.973 | <0.001 | >41.3 | 72.7 | 100.0 |
| ADCmean (s/mm2) | 1192 ± 625 | 1311 ± 219 | 0.884‡ | ||||||
| ADCmin (s/mm2) | 1093 ± 274 | 974 ± 334 | 0.733‡ | ||||||
| ADCsd (s/mm2) | 128 ± 25 | 134 ± 20 | 0.525‡ | ||||||
Independent-samples t-test, bold value indicates p-value is significant <0.05;
Independent-samples Mann-Whitney U-test, bold value indicates p-value is significant <0.05.
ADC, apparent diffusion coefficient; ADCmean, mean apparent diffusion coefficient; ADCmin, minimum apparent diffusion coefficient; ADCsd: standard deviation of apparent diffusion coefficient; AUC, area under receiver operating characteristic (ROC) curve; M0, no synchronous distant metastasis; M1, with synchronous distant metastasis; MTV, metabolic tumor volume; Se, sensitivity; Sp, specificity; SUV, standardized uptake values; SUVmax, maximum standardized uptake value; SUVmean, mean standardized uptake value; SUVpeak, the peak of SUV in 1 ml; SUVsd, standard deviation of standardized uptake value; TLG, total lesion glycolysis; 95% CI, 95% confidence interval.