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. 2020 Feb 25;11:103. doi: 10.3389/fphar.2020.00103

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Copyright © 2020 Luo, Zhang, Guo, Han, Ren and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ferulic acid (FA) inhibited mitophagy. (A) Mitophagy was detected by using MitoTracker Green and LysoTracker Red staining. (B) Quantitative analysis of lysosome fluorescence intensity. At least 50 cells from three independent experiments for each group were included; the counts were averaged. Scale bar: 100 µm. Data were expressed as the mean ± SEM (n = 3). **P < 0.01 versus the control group. ^#P < 0.05 and ^##P < 0.01 versus the hypoxia/reoxygenation (H/R) group. ^&&P < 0.01 versus the rapamycin group.