Table 2. Comparison of the incidence of top-ranked genetic alteration of this study with the TCGA database. Muse, mutect, somaticsniper, and varscan were used to determine true mutations.

SNUH pan-caner panel (n=20)				Gene	TCGA (n=496)
Truncating	Inframe	Missense	Sum		Truncating	Inframe	Missense	Sum
0 (0.0)	0 (0.0)	5 (25.0)	5 (25.0)	SPOP	1 (0.2)	0 (0.0)	50 (10.1)	51 (10.3)
1 (5.0)	0 (0.0)	3 (15.0)	4 (20.0)	KMT2D	16 (3.2)	1 (0.2)	12 (2.4)	29 (5.8)
0 (0.0)	0 (0.0)	3 (15.0)	3 (15.0)	MAP3K1	1 (0.2)	0 (0.0)	2 (0.4)	3 (0.6)
0 (0.0)	0 (0.0)	3 (15.0)	3 (15.0)	TSHR	0 (0.0)	0 (0.0)	1 (0.2)	1 (0.2)
0 (0.0)	1 (5.0)	2 (10.0)	3 (15.0)	FANCD2	1 (0.2)	0 (0.0)	1 (0.2)	2 (0.4)
0 (0.0)	0 (0.0)	3 (15.0)	3 (15.0)	ATM	3 (0.6)	1 (0.2)	13 (2.6)	17 (3.4)
0 (0.0)	0 (0.0)	3 (15.0)	3 (15.0)	FANCA	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)
0 (0.0)	1 (5.0)	2 (10.0)	3 (15.0)	BRAF	0 (0.0)	1 (0.2)	5 (1.0)	6 (1.2)
0 (0.0)	0 (0.0)	3 (15.0)	3 (15.0)	FANCG	0 (0.0)	0 (0.0)	1 (0.2)	1 (0.2)
0 (0.0)	0 (0.0)	2 (10.0)	2 (10.0)	NOTCH4	0 (0.0)	0 (0.0)	2 (0.4)	2 (0.4)
0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	ERG	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)
0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	NRG1	1 (0.2)	0 (0.0)	3 (0.6)	4 (0.8)
0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	AR	0 (0.0)	0 (0.0)	2 (0.4)	2 (0.4)

Values are presented as number (%).

SNUH, Seoul National University Hospital; TCGA, The Cancer Genome Atlas.