Table 3.
The results of searching the key pathways and their relevant compounds in cancer metabolic reprogramming.
| Pathway | Starting compound | Ending compound | Found/Not found |
|---|---|---|---|
| PPP | D-ribulose 5-phosphate |
D-xylulose 5-phosphate |
Found |
| Glycolysis | beta-D-fructofuranose 6-phosphate |
Fructose 1,6-bisphosphate |
Found |
| Fatty acid oxidation | Coenzyme A | Acetyl-CoA | Found |
| Fatty acid synthesis | – | – | Not found |
| Glutaminolysis | L-glutamine | L-aspartate | Found |
| ETC | NADH | NAD+ | Found |
| TCA cycle | acetyl-CoA | NADH | Found |
| Mitochondrial biogenesis | Pyruvate | (R)-lactate | Found |
“Found” means the corresponding pathway was identified by CaMeRe among the top three.