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. 2020 Feb 28;26(8):804–817. doi: 10.3748/wjg.v26.i8.804

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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ORM genes are highly expressed specifically in human liver tissues. A and B: The Human Protein Atlas project was used to test orosomucoid 1 (ORM1) (A) and ORM2 (B) expression levels in different tissues. Gene levels were determined by RPKM and RNA-seq. C and D: The difference in ORM gene expression between liver cancer/other tumors, liver/other normal tissues, liver cancer/adjacent normal liver tissues, and liver tumors/other adjacent normal tissues. The results are shown as differential ratios by logFC. RPKM: Reads Per Kilobase per Million mapped reads; FC: Fold change; HCC: Hepatocellular carcinoma; ORM1: Orosomucoid 1.