Table 1.
Demographic and clinical characteristics of patients, n (%)
| Variable |
All patients |
P value |
Matched patients |
P value | ||
| NAC and surgery (n = 36) | Surgery first (n = 108) | NAC and surgery (n = 36) | Surgery first (n = 36) | |||
| Age, yr (mean ± SD) | 52 ± 11 | 57 ± 12 | < 0.05 | 51.6 ± 11.4 | 49.9 ± 12.2 | 0.531 |
| Sex | 0.307 | 1 | ||||
| Male | 21 (58.3) | 75 (69.4) | 21 (58.3) | 21 (58.3) | ||
| Female | 15 (41.7) | 33 (30.6) | 15 (41.7) | 15 (41.7) | ||
| BMI, kg/m2 (mean ± SD) | 24.1 ± 50 | 23.7 ± 3.4 | 0.527 | 24.1 ± 5.0 | 23.6 ± 3.4 | 0.649 |
| ASA | 0.731 | 1 | ||||
| I-II | 34 (94.4) | 99 (91.7) | 34 (94.4) | 33 (91.7) | ||
| III-IV | 2 (5.6) | 9 (8.3) | 2 (5.6) | 3 (8.3) | ||
| Comorbidity | 0.152 | 1 | ||||
| Absent | 28 (77.8) | 68 (63.0) | 28 (77.8) | 27 (75.0) | ||
| Present | 8 (22.2) | 40 (37.0) | 8 (22.2) | 9 (25.0) | ||
| Tumor location | 0.069 | 0.896 | ||||
| Upper | 4 (11.1) | 32 (29.6) | 4 (11.1) | 5 (13.9) | ||
| Middle | 13 (36.1) | 36 (33.3) | 13 (36.1) | 14 (38.9) | ||
| Lower | 19 (52.8) | 40 (37.0) | 19 (52.8) | 17 (47.2) | ||
| Clinical T stage | 1 | 0.462 | ||||
| 3 | 15 (41.7) | 46 (42.6) | 15 (41.7) | 11 (30.6) | ||
| 4 | 21 (58.3) | 62 (57.4) | 21 (58.3) | 25 (69.4) | ||
| Clinical N stage | < 0.05 | 0.514 | ||||
| 0 | 4 (11.1) | 35 (32.4) | 4 (11.1) | 7 (19.4) | ||
| 1-3 | 32 (88.9) | 73 (67.6) | 32 (88.9) | 29 (80.6) | ||
| Clinical TNM stage | 0.181 | 0.829 | ||||
| IIB | 4 (11.1) | 27 (25.0) | 4 (11.1) | 6 (16.7) | ||
| III | 29 (80.6) | 70 (64.8) | 29 (80.6) | 28 (77.8) | ||
| IVA | 3 (8.3) | 11 (10.2) | 3 (8.3) | 2 (5.6) | ||
NAC: Neoadjuvant chemotherapy; BMI: Body mass index; ASA: American Society of Anesthesiologists.