Table 5.
Quality of life in the colostomy group and conservative group of chronic radiation proctopathy patients based on the EORTC QLQ-C30 scale
QLQ-C30 scale | Reference: Normal German population |
Colostomy group, n = 14, mean ± SD |
Conservative group, n = 25, mean ± SD |
||||||
Pretreat-ment | Follow-up | Δ(FU)-Pre2 | Signifi-cance1 | Pretreat-ment | Follow-up | Δ(FU)-Pre | Signifi-cance1 | ||
Global health | 63.2 | 23.1 ± 15.1 | 63.1 ± 18.3 | 40 | < 0.001 | 47.1 ± 21.5 | 62.3 ± 25.0 | 15.2 | 0.033 |
Physical function | 82.6 | 50.7 ± 17.8 | 87.1 ± 13.7 | 36.4 | < 0.001 | 78.0 ± 22.7 | 78.6 ± 26.1 | 0.6 | 0.856 |
Role function | 75 | 34.3 ± 23.9 | 89.3 ± 20.5 | 55 | < 0.001 | 77.5 ± 24.9 | 77.5 ± 29.1 | 0 | 0.775 |
Emotional function | 62.2 | 46.3 ± 27.4 | 85.7 ± 14.9 | 39.4 | < 0.001 | 75.7 ± 17.6 | 80.8 ± 23.8 | 5.1 | 0.384 |
Cognition function | 81.3 | 92.6 ± 12.7 | 95.2 ± 9.8 | 2.6 | 1.0 | 94.2 ± 15.6 | 95.7 ± 9.0 | 1.5 | 0.798 |
Social function | 78.4 | 43.5 ± 28.9 | 79.8 ± 18.0 | 36.3 | < 0.001 | 91.3 ± 20.6 | 89.1 ± 21.1 | -2.2 | 0.916 |
Fatigue | 34.1 | 72.8 ± 12.9 | 10.3 ± 18.5 | -62.5 | < 0.001 | 26.6 ± 24.1 | 23.2 ± 27.2 | -3.4 | 0.695 |
Nausea/ vomiting | 5.7 | 4.6 ± 15.5 | 0 ± 0 | -4.6 | - | 5.1 ± 15.4 | 6.5 ± 16.5 | 1.4 | 0.655 |
Pain | 33.1 | 44.4 ± 28.3 | 9.5 ± 15.1 | -34.9 | < 0.001 | 14.5 ± 21.5 | 11.6 ± 18.4 | -2.9 | 0.481 |
Dyspnea | 18.8 | 42.6 ± 31.0 | 4.8 ± 11.7 | -37.8 | < 0.001 | 14.5 ± 19.7 | 8.7 ± 18.0 | -5.8 | 0.210 |
Insomnia | 38.5 | 48.1 ± 35.5 | 11.9 ± 20.3 | -36.2 | < 0.001 | 21.7 ± 21.6 | 26.1 ± 31.7 | 4.4 | 0.287 |
Appetite loss | 9.4 | 22.2 ± 27.2 | 0 ± 0 | -22.2 | - | 10.1 ± 25.5 | 8.7 ± 18.0 | -1.4 | 0.785 |
Constipation | 9.1 | 9.3 ± 14.9 | 9.5 ± 15.1 | -0.2 | 1.0 | 8.7 ± 20.6 | 7.2 ± 22.4 | -1.5 | 0.414 |
Diarrhea | 9.2 | 33.3 ± 33.3 | 9.5 ± 26.5 | -23.8 | < 0.001 | 11.6 ± 23.8 | 2.9 ± 9.6 | -8.7 | 0.078 |
Financial difficulties | 17.1 | 59.3 ± 26.2 | 23.8 ± 31.9 | -35.5 | < 0.001 | 26.1 ± 31.7 | 24.6 ± 30.5 | -1.5 | 0.595 |
Wilcoxon rank-sum test.
Point (follow-up) – point (pretreatment). Δ(FU): Change in follow-up; SD: Standard deviation.