Table 3.
Univariate and multivariate Cox regression analyese of prognostic factors and overall survival of patients with hepatocellular carcinoma from The Cancer Genome Atlas database
| Variable |
Univariate analysis |
Multivariate analysis |
||||
| HR | 95%CI | P value | HR | 95%CI | P value | |
| Risk score | 11.37 | 5.49-23.56 | < 0.001 | 8.99 | 2.53-32.01 | 0.001 |
| TNM stage | 1.79 | 1.45-2.22 | < 0.001 | 1.24 | 0.89-1.75 | 0.209 |
| Age | 1.01 | 0.99-1.02 | 0.254 | |||
| Gender | 0.79 | 0.55-1.13 | 0.192 | |||
| Race | 1.13 | 0.94-1.37 | 0.196 | |||
| Child-Pugh score | 1.69 | 0.93-3.07 | 0.084 | |||
| ECGO performance status | 2.41 | 1.91-3.04 | < 0.001 | 1.74 | 1.16-2.63 | 0.008 |
| AFP | 1 | 1-1 | 0.443 | |||
| Fibrosis ishak score | 0.91 | 0.78-1.07 | 0.253 | |||
| Histologic grade | 1.1 | 0.86-1.4 | 0.445 | |||
| Vascular invasion | 1.47 | 1.06-2.06 | 0.022 | 1.16 | 0.75-1.79 | 0.511 |
| Hepatitis virus infection | 0.45 | 0.3-0.68 | < 0.001 | 0.81 | 0.45-1.46 | 0.477 |
| Alcohol consumption | 1.1 | 0.75-1.62 | 0.616 | |||
HR: Hazard ratio; CI: Confidential interval; ECOG: Eastern Cooperative Oncology Group.