Fig. 7.

Relationship of weighted gene coexpression network analysis (WGCNA) results and percent epithelial proliferation for WT V vs. Ezh2cKO V comparison. Modules identified in Supplemental Fig. S1 were correlated with epithelial proliferation (Fig. 1). Each row corresponds to a module eigengene (ME), and colors represent the correlation coefficient between the ME and percentage of uterine epithelial cell proliferation. Numbers at the top of rows represents degree of correlation, and values with a negative integer indicate an inverse correlation with epithelial proliferation. Two color modules, Green and Sky Blue 3, positively correlated with epithelial proliferation (demarcated with boxes). A legend that ranges from blue to red shades (−1 to 1, respectively) is included to the right of the figure. These colors coincide with degree of correlation with darker blue representing strong negative correlation between an individual ME and proliferation and those ME more intensely red indicating a positive correlation. This is evident in the two ME, Green and Sky Blue 3 boxes, that are colored in dark red to indicate that the genes within these modules are positively associated with proliferation.