Table 7.

Selective pathways associated with the Sky Blue3 and Green color modules for WT V vs. Ezh2cKO V comparison

Module Color	Source	Pathway	FDR
Sky blue	GO:BP	metabolic process	1.55E-06
	GO:BP	regulation of cellular metabolic process	9.84E-06
	GO:BP	regulation of metabolic process	2.65E-05
	GO:BP	apoptotic process	0.000499702
	GO:BP	regulation of MAPK cascade	0.009607817
Green	GO:MF	steroid hormone receptor binding	0.000040182
	GO:MF	nuclear hormone receptor binding	5.12E-05
	GO:MF	histone binding	8.65E-05
	GO:MF	hormone receptor binding	0.000184918
	GO:BP	histone acetylation	0.00134373
	GO:BP	intracellular steroid hormone receptor signaling pathway	0.00141134
	GO:BP	steroid hormone-mediated signaling pathway	0.002336833
	GO:BP	cellular hormone metabolic process	0.002708761
	KEGG	PI3K-Akt signaling pathway	5.73E-05
	KEGG	choline metabolism in cancer	5.73E-05
	KEGG	pathways in cancer	0.000617863
	KEGG	thyroid hormone signaling pathway	0.001765468
	KEGG	JAK-STAT signaling pathway	0.002660921
	KEGG	endocrine resistance	0.003160081
	KEGG	estrogen signaling pathway	0.00363483
	KEGG	prolactin signaling pathway	0.005348187
	KEGG	TNF signaling pathway	0.005348187
	KEGG	MAPK signaling pathway	0.005348187
	REAC	signaling by receptor tyrosine kinases	1.24E-06
	REAC	immune system	0.000106784
	REAC	PIP3 activates AKT signaling	0.000106784
	REAC	MAPK1/MAPK3 signaling	0.000123755
	REAC	PI5P, PP2A, and IER3 regulate PI3K/AKT signaling	0.000397045
	REAC	PI3K cascade	0.002000441
	REAC	PI3K/AKT activation	0.002643746
	REAC	IGF1R signaling cascade	0.002643746
	REAC	signaling by insulin receptor	0.002643746
	REAC	signaling by type 1 insulin-like growth factor 1 receptor (IGF1R)	0.002828781
	REAC	insulin receptor signaling cascade	0.00302286
	WP	EGFR1 signaling pathway	0.001556579
	WP	insulin signaling	0.002021013
	WP	IL-3 signaling pathway	0.004400538

Italicized pathways are mentioned in results.