. 2019 Nov 25;318(2):G288–G297. doi: 10.1152/ajpgi.00011.2019

Table 3.

Brachyspira hyodysenteriae and Brachyspira hampsonii decrease basal J_ms and net Na⁺ absorption during ²²Na equilibration in the apex of the porcine spiral colon

	J^Na+, µeq·cm²·h
	M-S		S-M		Net		TEER, ohm·cm²		Potential Difference, mV
	Basal	80 Min	Basal	80 Min	Basal	80 Minutes	Basal	80 Min	Basal	80 Min
Control	17.38 ± 3.36^a	59.32 ± 18.10^a	14.83± 3.05^a	40.94 ± 7.70^a	2.59 ± 4.62^a	17.01 ± 14.61^a	60.62 ± 32.94^a	58.82 ± 28.39^a	0.1 ± 1.4^a	0.0 ± 1.5^a
B. hyo	10.14 ± 11.12^b	37.15 ± 22.53^b	10.23 ± 9.79^a	40.62 ± 15.11^a^,^b	−0.78 ± 4.85^b	−0.78 ± 11.14^b	58.16 ± 17.46^a	52.38 ± 13.23^b	1.0 ± 1.2^b	0.8 ± 1.0^b
B. hamp	11.50 ± 15.78^b	31.95 ± 19.53^b	8.91 ± 16.80^a	30.86 ± 16.43^c	1.15 ± 4.69^a	0.65 ± 12.29^b	55.40 ± 26.53^a	49.56 ± 19.23^b	1.0 ± 1.0^b	0.7 ± 1.0^b

Data are median ± interquartile range, analyzed using Kruskal-Wallis one-way ANOVA and Dunn’s post hoc; n = 12 ctrl, n = 12 B. hyodysenteriae, and n = 12 B. hampsonii. Basal mucosal-to-serosal flux (J_ms), serosal-to-mucosal flux (J_sm), and net flux rates during ²²Na equilibration across apex colonic segments from control, B. hyodysenteriae, and B. hampsonii-diseased pigs were measured immediately following mounting and clamping of the tissue (basal) and at the end of the 80-min equilibration period. M-S, unidirectional mucosal-to-serosal ²²Na flux; S-M, unidirectional serosal-to-mucosal ²²Na flux; Net, net ²²Na flux; TEER, transepithelial electric resistance. Significant differences within tissue groups across the basal and 80-min time points are in underlined. Significantly different values within each group are marked in bold. Each value marked with a different superscript letter differs by at least P < 0.05 compared with other groups at the same time points.