Table 3.
Summary statistics per mouse strain
| Strain |
|||||
|---|---|---|---|---|---|
| Measurement | Unit | B6C3F1 | BALB/C | C57BL/6 | CD-1 |
| Body weight | g | 21.7 ± 1.8 | 23.4 ± 1.5 | 22.7 ± 1.7 | 24.4 ± 1.0 |
| Respiratory rate | per min | 200 ± 44 | 245 ± 22 | 262 ± 21 | 189 ± 52 |
| Tidal volume | mL | 0.18 ± 0.05 | 0.25 ± 0.10 | 0.26 ± 0.03 | 0.31 ± 0.03 |
| Minute ventilation | mL/min | 37.4 ± 14.9 | 62.6 ± 26.1 | 67.1 ± 8.1 | 59.9 ± 18.8 |
| Inspiration to expiration ratio | 0.99 ± 0.11 | 0.88 ± 0.05 | 0.87 ± 0.08 | 0.90 ± 0.07 | |
| Age | wk | M:7, F:8 | M:7, F:11 | M:7, F:12 | M:5, F:6 |
| Lung volume | mm3 | 1,104.6 ± 39.3 | 1,093.2 ± 132.5 | 1,155.9 ± 123.7 | 1,195.6 ± 30.4 |
| Left lobe volume | mm3 | 363.7 ± 17.0 | 375.8 ± 48.8 | 379.2 ± 40.0 | 379.4 ± 21.9 |
| Cranial lobe volume | mm3 | 187.6 ± 12.6 | 185.4 ± 23.9 | 190.8 ± 31.6 | 230.8 ± 15.9 |
| Middle lobe volume | mm3 | 133.9 ± 10.0 | 139.2 ± 16.8 | 139.3 ± 14.1 | 150.3 ± 5.1 |
| Caudal lobe volume | mm3 | 310.1 ± 14.8 | 296.3 ± 37.8 | 333.9 ± 35.0 | 322.6 ± 13.3 |
| Accessory lobe volume | mm3 | 109.3 ± 6.6 | 96.5 ± 15.5 | 112.7 ± 7.1 | 112.5 ± 13.9 |
| Number of sublobes | 54.1 ± 1.2 | 54.0 ± 2.4 | 53.6 ± 1.9 | 54.4 ± 2.0 | |
| Sublobe volume | mm3 | 19.8 ± 20.5 | 19.8 ± 20.0 | 20.9 ± 22.0 | 21.4 ± 21.4 |
| Number of near-acini | 362.0 ± 52.8 | 348.7 ± 46.2 | 350.2 ± 91.0 | 390.4 ± 50.6 | |
| Near-acini volume | mm3 | 2.9 ± 1.8 | 3.0 ± 1.9 | 3.1 ± 2.0 | 2.9 ± 1.9 |
| Tree length | mm | 627.4 ± 8.1 | 567.9 ± 51.3 | 646.2 ± 46.7 | 554.8 ± 54.1 |
| Number of segments | 1,773.4 ± 219.8 | 1,448.5 ± 168.1 | 1,900.2 ± 264.2 | 1,379.0 ± 214.4 | |
| Number of outlet regions | 2,075.8 ± 227.5 | 1,972.1 ± 248.5 | 2,092.1 ± 305.9 | 1,700.7 ± 301.8 | |
| Outlet region area | mm2 | 0.012 ± 0.007 | 0.015 ± 0.011 | 0.012 ± 0.008 | 0.013 ± 0.009 |
| Branching angle | degree | 43.7 ± 20.2 | 42.8 ± 21.1 | 43.5 ± 20.1 | 43.9 ± 21.4 |
Measurement values are provided in mean ± SD format. F, female; M, male.