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Pressor effects (A and B) and heart rate (HR) (C) changes induced by ANG II in maternal normal fat diet (NFD) offspring and high-fat diet (HFD) offspring with pretreatment with captopril (Cap). The enhanced pressor effect in HFD offspring was attenuated by Cap pretreatment. (n = 6/group; two-way ANOVA, *P < 0.05 vs. baseline; #P < 0.05 vs. NFD offspring or HFD offspring with Cap pretreatment). MAP, mean arterial pressure.
