Fig. 4.

Quantitative comparison of the mRNA expression of renin-angiotensin system components, proinflammatory cytokines and NADPH oxidase in the lamina terminalis (LT) and paraventricular nucleus (PVN) in maternal normal fat diet (NFD) offspring and high-fat diet (HFD) offspring with pretreatment with pentoxifylline (PTX) before ANG II infusion (A and B). (n = 5/group; one-way ANOVA, *P < 0.05 vs. NFD offspring; #P < 0.05 vs. HFD-offspring without pretreatment). AGT, angiotensinogen; ACE, angiotensin-converting enzyme; AT1-R, ANG II type 1 receptor; TNF-α, tumor necrosis factor-α; IL, interleukin; NOX2, NADPH oxidase.