Fig. 10.

AMI-1 inhibits renal fibroblast proliferation in the kidneys after unilateral ureteral obstruction (UUO) injury. A: after UUO injury, collected kidney tissue was used for costaining with antibodies to α-smooth muscle actin (α-SMA) and proliferating cell nuclear antigen (PCNA) (magnification: ×200). B: interstitial cells with positive staining for both α-SMA and PCNA were counted in 10 high-power fields and expressed as means ± SD. *P < 0.05 and **P < 0.01 vs. the control group or other groups as indicated. Scale bar = 200 μm. Yellow arrows indicate small blood arteries; white arrows indicate proliferating myofibroblasts.